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Can Omega-3 Fatty Acids Prevent Psychotic Disorder?

Low levels of omega-3 associated with higher risk of psychosis.

New research has found that adolescents with higher levels of an omega-3 fatty acid in their blood were less likely to develop psychotic disorder in early adulthood, suggesting that it may have a potential preventative effect of reducing the risk of psychosis.

Can Fish Oil Supplements – Prevent Psychotic Disorder?

Omega-3 Fish Oil Supplements

Low levels of omega-3 associated with higher risk of psychosis.

New research has found that adolescents with higher levels of an omega-3 fatty acid in their blood were less likely to develop psychotic disorder in early adulthood, suggesting that it may have a potential preventative effect of reducing the risk of psychosis.

The study, led by researchers from RCSI University of Medicine and Health Sciences, is published in Translational Psychiatry.

Over 3,800 individuals in Bristol’s Children of the 90s health study were assessed for psychotic disorder, depressive disorder and generalized anxiety disorder at age 17 and at age 24.

During these assessments, blood samples were collected, and the researchers measured the levels of omega-6 fatty acids, which generally increase inflammation in the body, fatty acids, which generally reduce inflammation.New research has found that adolescents with higher levels of an omega-3 fatty acid in their blood were less likely to develop psychotic disorder in early adulthood, suggesting that it may have a potential preventative effect of reducing the risk of psychosis. Credit: RCSI University of Medicine and Health Sciences

While there was little evidence that fatty acids were associated with mental disorders at age 17, the researchers found that 24 year olds with psychotic disorder, depressive disorder and generalized anxiety disorder had higher levels of omega-6 than omega-3 fatty acids compared to those without these disorders.

The researchers also found that 24 year olds with psychotic disorder had lower levels of DHA, an omega-3 fatty acid typically found in oily fish or dietary supplements, than 24 year olds without psychotic disorder. In a group of over 2,700 individuals who were tracked over time, adolescents with higher levels of DHA at age 17 were 56% less likely to develop psychotic disorder seven years later at age 24. This suggests that DHA in adolescence may have a potential preventative effect of reducing the risk of psychosis in early adulthood.

These results remained consistent when accounting for other factors such as sex, body mass index, tobacco smoking, and socio-economic status.

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